The Effect of Chloroquine on Immune Activation and Interferon Signatures Associated with HIV-1

Immune activation associated with HIV-1 infection contributes to morbidity and mortality. We studied whether chloroquine, through Toll-like receptor (TLR) antagonist properties, could reduce immune activation thought to be driven by TLR ligands, such as gut-derived bacterial elements and HIV-1 RNAs....

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:AIDS Res Hum Retroviruses
Main Authors: Jacobson, Jeffrey M., Bosinger, Steven E., Kang, Minhee, Belaunzaran-Zamudio, Pablo, Matining, Roy M., Wilson, Cara C., Flexner, Charles, Clagett, Brian, Plants, Jill, Read, Sarah, Purdue, Lynette, Myers, Laurie, Boone, Linda, Tebas, Pablo, Kumar, Princy, Clifford, David, Douek, Daniel, Silvestri, Guido, Landay, Alan L., Lederman, Michael M.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2016
Assuntos:
Clinical Trials/Clinical Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931767/
https://ncbi.nlm.nih.gov/pubmed/26935044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2015.0336
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados