HIV-1 Group O Genotypes and Phenotypes: Relationship to Fitness and Susceptibility to Antiretroviral Drugs

Despite only 30,000 group O HIV-1 infections, a similar genetic diversity is observed among the O subgroups H (head) and T (tail) (previously described as subtypes A, B) as in the 9 group M subtypes (A–K). Group O isolates bearing a cysteine at reverse transcriptase (RT) position 181, predominantly...

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Detalhes bibliográficos
Publicado no:AIDS Res Hum Retroviruses
Main Authors: Tebit, Denis M., Patel, Hamish, Ratcliff, Annette, Alessandri, Elodie, Liu, Joseph, Carpenter, Crystal, Plantier, Jean-Christophe, Arts, Eric J.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2016
Assuntos:
Preclinical Studies/Drug Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931737/
https://ncbi.nlm.nih.gov/pubmed/26861573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2015.0318
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