Severe psychosocial deprivation in early childhood is associated with increased DNA methylation across a region spanning the transcription start site of CYP2E1

Exposure to adverse rearing environments including institutional deprivation and severe childhood abuse is associated with an increased risk for mental and physical health problems across the lifespan. Although the mechanisms mediating these effects are not known, recent work in rodent models sugges...

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Detalhes bibliográficos
Publicado no:Transl Psychiatry
Main Authors: Kumsta, R, Marzi, S J, Viana, J, Dempster, E L, Crawford, B, Rutter, M, Mill, J, Sonuga-Barke, E J S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931613/
https://ncbi.nlm.nih.gov/pubmed/27271856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2016.95
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