Nucleus accumbens deep-brain stimulation efficacy in ACTH-pretreated rats: alterations in mitochondrial function relate to antidepressant-like effects

Mitochondrial dysfunction has a critical role in the pathophysiology of mood disorders and treatment response. To investigate this, we established an animal model exhibiting a state of antidepressant treatment resistance in male Wistar rats using 21 days of adrenocorticotropic hormone (ACTH) adminis...

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Detalhes bibliográficos
Publicado no:Transl Psychiatry
Main Authors: Kim, Y, McGee, S, Czeczor, J K, Walker, A J, Kale, R P, Kouzani, A Z, Walder, K, Berk, M, Tye, S J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931612/
https://ncbi.nlm.nih.gov/pubmed/27327257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2016.84
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