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A mega-analysis of fixed-dose trials reveals dose-dependency and a rapid onset of action for the antidepressant effect of three selective serotonin reuptake inhibitors

The possible dose-dependency for the antidepressant effect of selective serotonin reuptake inhibitors (SSRIs) remains controversial. We believe we have conducted the first comprehensive patient-level mega-analysis exploring this issue, one incentive being to address the possibility that inclusion of...

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Publicado en:Transl Psychiatry
Autores principales: Hieronymus, F, Nilsson, S, Eriksson, E
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931602/
https://ncbi.nlm.nih.gov/pubmed/27271860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2016.104
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