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Mpath maps multi-branching single-cell trajectories revealing progenitor cell progression during development

Single-cell RNA-sequencing offers unprecedented resolution of the continuum of state transition during cell differentiation and development. However, tools for constructing multi-branching cell lineages from single-cell data are limited. Here we present Mpath, an algorithm that derives multi-branchi...

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Publicat a:Nat Commun
Autors principals: Chen, Jinmiao, Schlitzer, Andreas, Chakarov, Svetoslav, Ginhoux, Florent, Poidinger, Michael
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931327/
https://ncbi.nlm.nih.gov/pubmed/27356503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11988
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