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Memory of cell shape biases stochastic fate decision-making despite mitotic rounding

Cell shape influences function, and the current model suggests that such shape effect is transient. However, cells dynamically change their shapes, thus, the critical question is whether shape information remains influential on future cell function even after the original shape is lost. We address t...

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Pubblicato in:Nat Commun
Autori principali: Akanuma, Takashi, Chen, Cong, Sato, Tetsuo, Merks, Roeland M. H., Sato, Thomas N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931277/
https://ncbi.nlm.nih.gov/pubmed/27349214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11963
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