SARI inhibits angiogenesis and tumour growth of human colon cancer through directly targeting ceruloplasmin

SARI, also called as BATF2, belongs to the BATF family and has been implicated in cancer cell growth inhibition. However, the role and mechanism of SARI in tumour angiogenesis are elusive. Here we demonstrate that SARI deficiency facilitates AOM/DSS-induced colonic tumorigenesis in mice. We show tha...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Dai, Lei, Cui, Xueliang, Zhang, Xin, Cheng, Lin, Liu, Yi, Yang, Yang, Fan, Ping, Wang, Qingnan, Lin, Yi, Zhang, Junfeng, Li, Chunlei, Mao, Ying, Wang, Qin, Su, Xiaolan, Zhang, Shuang, Peng, Yong, Yang, Hanshuo, Hu, Xun, Yang, Jinliang, Huang, Meijuan, Xiang, Rong, Yu, Dechao, Zhou, Zongguang, Wei, Yuquan, Deng, Hongxin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931276/
https://ncbi.nlm.nih.gov/pubmed/27353863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11996
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