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Mitochondrial-targeted Aryl Hydrocarbon Receptor and the Impact of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin on Cellular Respiration and the Mitochondrial Proteome

The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor within the Per-Arnt-Sim (PAS) domain superfamily. Exposure to the most potent AHR ligand, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), is associated with various pathological effects including metabolic syndrome. While res...

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Detalhes bibliográficos
Publicado no:Toxicol Appl Pharmacol
Main Authors: Hwang, Hye Jin, Dornbos, Peter, Steidemann, Michelle, Dunivin, Taylor K., Rizzo, Mike, LaPres, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930739/
https://ncbi.nlm.nih.gov/pubmed/27105554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2016.04.005
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