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Targeting the Thrombin Receptor Modulates Inflammation and Astrogliosis to Improve Recovery after Spinal Cord Injury

The deregulation of serine protease activity is a common feature of neurological injury, but little is known regarding their mechanisms of action or whether they can be targeted to facilitate repair. In this study we demonstrate that the thrombin receptor (Protease Activated Receptor 1, (PAR1)) serv...

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Détails bibliographiques
Publié dans:Neurobiol Dis
Auteurs principaux: Radulovic, Maja, Yoon, Hyesook, Wu, Jianmin, Mustafa, Karim, Scarisbrick, Isobel A.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930708/
https://ncbi.nlm.nih.gov/pubmed/27145117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2016.04.010
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