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Loss of BMP receptor type 1A in murine adipose tissue attenuates age-related onset of insulin resistance

AIMS/HYPOTHESIS: Adipose tissue dysfunction is a prime risk factor for the development of metabolic disease. Bone morphogenetic proteins (BMPs) have previously been implicated in adipocyte formation. Here, we investigate the role of BMP signalling in adipose tissue health and systemic glucose homeos...

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Détails bibliographiques
Publié dans:Diabetologia
Auteurs principaux: Schulz, Tim J., Graja, Antonia, Huang, Tian Lian, Xue, Ruidan, An, Ding, Poehle-Kronawitter, Sophie, Lynes, Matthew D., Tolkachov, Alexander, O’Sullivan, Lindsay E., Hirshman, Michael F., Schupp, Michael, Goodyear, Laurie J., Mishina, Yuji, Tseng, Yu-Hua
Format: Artigo
Langue:Inglês
Publié: Springer Berlin Heidelberg 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930470/
https://ncbi.nlm.nih.gov/pubmed/27209464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-016-3990-8
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