The Role of Steroid Receptor Coactivators in Hormone Dependent Cancers and Their Potential as Therapeutic Targets

Steroid receptor coactivator (SRC) family members (SRC-1, SRC-2, SRC-3) interact with nuclear receptors (NRs) and many transcription factors to enhance target gene transcription. Deregulation of SRCs is widely implicated in NR mediated diseases, especially hormone dependent cancers. By integrating s...

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Bibliografiske detaljer
Udgivet i:Horm Cancer
Main Authors: Wang, Lei, Lonard, David M., O’Malley, Bert W.
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2016
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930410/
https://ncbi.nlm.nih.gov/pubmed/27125199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12672-016-0261-6
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