NOVA2-mediated RNA regulation is required for axonal pathfinding during development

The neuron specific RNA-binding proteins NOVA1 and NOVA2 are highly homologous alternative splicing regulators. NOVA proteins regulate at least 700 alternative splicing events in vivo, yet relatively little is known about the biologic consequences of NOVA action and in particular about functional di...

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Vydáno v:eLife
Hlavní autoři: Saito, Yuhki, Miranda-Rottmann, Soledad, Ruggiu, Matteo, Park, Christopher Y, Fak, John J, Zhong, Ru, Duncan, Jeremy S, Fabella, Brian A, Junge, Harald J, Chen, Zhe, Araya, Roberto, Fritzsch, Bernd, Hudspeth, A J, Darnell, Robert B
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2016
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930328/
https://ncbi.nlm.nih.gov/pubmed/27223325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.14371
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