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Inhibition of Wnt Signaling by Silymarin in Human Colorectal Cancer Cells

Silymarin from milk thistle (Silybum marianum) has been reported to show an anti-cancer activity. In previous study, we reported that silymarin induces cyclin D1 proteasomal degradation through NF-κB-mediated threonine-286 phosphorylation. However, mechanism for the inhibition of Wnt signaling by si...

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Bibliographic Details
Published in:Biomol Ther (Seoul)
Main Authors: Eo, Hyun Ji, Park, Gwang Hun, Jeong, Jin Boo
Format: Artigo
Language:Inglês
Published: The Korean Society of Applied Pharmacology 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930281/
https://ncbi.nlm.nih.gov/pubmed/27068260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2015.154
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