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Antioxidant defense by thioredoxin can occur independently of canonical thiol-disulfide oxidoreductase enzymatic activity

The thiol-disulfide oxidoreductase CXXC catalytic domain of thioredoxin contributes to antioxidant defense in phylogenetically diverse organisms. We find that while the oxidoreductase activity of thioredoxin-1 protects Salmonella enterica serovar Typhimurium from hydrogen peroxide in vitro, it does...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Song, Miryoung, Kim, Ju-Sim, Liu, Lin, Husain, Maroof, Vázquez-Torres, Andrés
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930247/
https://ncbi.nlm.nih.gov/pubmed/26997275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.02.066
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