A novel imidazopyridine derivative, X22, attenuates sepsis-induced lung and liver injury by inhibiting the inflammatory response in vitro and in vivo

Sepsis remains a leading cause of death worldwide. Despite years of extensive research, effective drugs to treat sepsis in the clinic are lacking. In this study, we found a novel imidazopyridine derivative, X22, which has powerful anti-inflammatory activity. X22 dose-dependently inhibited lipopolysa...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Ge, Xiangting, Feng, Zhiguo, Xu, Tingting, Wu, Beibei, Chen, Hongjin, Xu, Fengli, Fu, Lili, Shan, Xiaoou, Dai, Yuanrong, Zhang, Yali, Liang, Guang
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930233/
https://ncbi.nlm.nih.gov/pubmed/27390516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S101449
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