Novel Mechanisms of Compromised Lymphatic Endothelial Cell Homeostasis in Obesity: The Role of Leptin in Lymphatic Endothelial Cell Tube Formation and Proliferation

Leptin is a hormone produced by adipose tissue that regulates various physiological processes. Recent studies have shown that the level of circulating leptin is elevated in obese patients and have suggested a relationship between obesity and postoperative lymphedema. However, the mechanisms by which...

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Udgivet i:PLoS One
Main Authors: Sato, Akinori, Kamekura, Ryuta, Kawata, Koji, Kawada, Masaya, Jitsukawa, Sumito, Yamashita, Keiji, Sato, Noriyuki, Himi, Tetsuo, Ichimiya, Shingo
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930203/
https://ncbi.nlm.nih.gov/pubmed/27366905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158408
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