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Hepatitis C Virus Core Protein Promotes miR-122 Destabilization by Inhibiting GLD-2

The liver-specific microRNA miR-122, which has essential roles in liver development and metabolism, is a key proviral factor for hepatitis C virus (HCV). Despite its crucial role in the liver and HCV life cycle, little is known about the molecular mechanism of miR-122 expression regulation by HCV in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:PLoS Pathog
Hauptverfasser: Kim, Geon-Woo, Lee, Seung-Hoon, Cho, Hee, Kim, Minwoo, Shin, Eui-Cheol, Oh, Jong-Won
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930175/
https://ncbi.nlm.nih.gov/pubmed/27366906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005714
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