Reduced protein synthesis in schizophrenia patient-derived olfactory cells

Human olfactory neurosphere-derived (ONS) cells have the potential to provide novel insights into the cellular pathology of schizophrenia. We used discovery-based proteomics and targeted functional analyses to reveal reductions in 17 ribosomal proteins, with an 18% decrease in the total ribosomal si...

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Detalhes bibliográficos
Publicado no:Transl Psychiatry
Main Authors: English, J A, Fan, Y, Föcking, M, Lopez, L M, Hryniewiecka, M, Wynne, K, Dicker, P, Matigian, N, Cagney, G, Mackay-Sim, A, Cotter, D R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930119/
https://ncbi.nlm.nih.gov/pubmed/26485547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2015.119
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