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No significant impact of IFN-γ pathway gene variants on tuberculosis susceptibility in a West African population

The concept of interferon-γ (IFN-γ) having a central role in cell-mediated immune defence to Mycobacterium tuberculosis has long been proposed. Observations made through early candidate gene studies of constituents of the IFN-γ pathway have identified moderately associated variants associated with r...

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Библиографические подробности
Опубликовано в: :Eur J Hum Genet
Главные авторы: Meyer, Christian G, Intemann, Christopher D, Förster, Birgit, Owusu-Dabo, Ellis, Franke, Andre, Horstmann, Rolf D, Thye, Thorsten
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930082/
https://ncbi.nlm.nih.gov/pubmed/26242990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2015.172
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