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Increased genetic risk for obesity in premature coronary artery disease

There is ongoing controversy as to whether obesity confers risk for CAD independently of associated risk factors including diabetes mellitus. We have carried out a Mendelian randomization study using a genetic risk score (GRS) for body mass index (BMI) based on 35 risk alleles to investigate this qu...

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Detalhes bibliográficos
Publicado no:Eur J Hum Genet
Main Authors: Cole, Christopher B, Nikpay, Majid, Stewart, Alexandre FR, McPherson, Ruth
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929880/
https://ncbi.nlm.nih.gov/pubmed/26220701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2015.162
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