A Common CD36 Variant Influences Endothelial Function and Response to Treatment with Phosphodiesterase 5 Inhibition

CONTEXT: The scavenger receptor CD36 influences the endothelial nitric oxide-cGMP pathway in vitro. Genetic variants that alter CD36 level are common in African Americans (AAs), a population at high risk of endothelial dysfunction. OBJECTIVE: To examine if the minor allele (G) of coding CD36 variant...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Shibao, Cyndya A., Celedonio, Jorge E., Ramirez, Claudia E., Love-Gregory, Latisha, Arnold, Amy C., Choi, Leena, Okamoto, Luis E., Gamboa, Alfredo, Biaggioni, Italo, Abumrad, Naji N., Abumrad, Nada A.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2016
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929841/
https://ncbi.nlm.nih.gov/pubmed/27144937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2016-1294
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