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Efficacy, safety, and tolerability of lacosamide in patients with gain-of-function Na(v)1.7 mutation-related small fiber neuropathy: study protocol of a randomized controlled trial–the LENSS study
BACKGROUND: Small fiber neuropathy generally leads to considerable pain and autonomic symptoms. Gain-of-function mutations in the SCN9A- gene, which codes for the Na(v)1.7 voltage-gated sodium channel, have been reported in small fiber neuropathy, suggesting an underlying genetic basis in a subset o...
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| Pubblicato in: | Trials |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4929773/ https://ncbi.nlm.nih.gov/pubmed/27363506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-016-1430-1 |
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