Salicylic acid analogues as chemical exchange saturation transfer MRI contrast agents for the assessment of brain perfusion territory and blood–brain barrier opening after intra-arterial infusion

The blood–brain barrier (BBB) is a major obstacle for drug delivery to the brain. Predicted, focal opening of the BBB through intra-arterial infusion of hyperosmolar mannitol is feasible, but there is a need to facilitate imaging techniques (e.g. MRI) to guide interventional procedures and assess th...

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Bibliographische Detailangaben
Veröffentlicht in:J Cereb Blood Flow Metab
Hauptverfasser: Song, Xiaolei, Walczak, Piotr, He, Xiaowei, Yang, Xing, Pearl, Monica, Bulte, Jeff WM, Pomper, Martin G, McMahon, Michael T, Janowski, Mirosław
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2016
Schlagworte:
Brief Communications
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929703/
https://ncbi.nlm.nih.gov/pubmed/26980755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X16637882
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