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Salicylic acid analogues as chemical exchange saturation transfer MRI contrast agents for the assessment of brain perfusion territory and blood–brain barrier opening after intra-arterial infusion
The blood–brain barrier (BBB) is a major obstacle for drug delivery to the brain. Predicted, focal opening of the BBB through intra-arterial infusion of hyperosmolar mannitol is feasible, but there is a need to facilitate imaging techniques (e.g. MRI) to guide interventional procedures and assess th...
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| Publicado no: | J Cereb Blood Flow Metab |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4929703/ https://ncbi.nlm.nih.gov/pubmed/26980755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X16637882 |
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