BACE-1 is expressed in the blood–brain barrier endothelium and is upregulated in a murine model of Alzheimer’s disease

Endothelial cells of the blood–brain barrier form a structural and functional barrier maintaining brain homeostasis via paracellular tight junctions and specific transporters such as P-glycoprotein. The blood–brain barrier is responsible for negligible bioavailability of many neuroprotective drugs....

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Cereb Blood Flow Metab
Autori principali: Devraj, Kavi, Poznanovic, Slobodan, Spahn, Christoph, Schwall, Gerhard, Harter, Patrick N, Mittelbronn, Michel, Antoniello, Katia, Paganetti, Paolo, Muhs, Andreas, Heilemann, Mike, Hawkins, Richard A, Schrattenholz, André, Liebner, Stefan
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publications 2015
Soggetti:
Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929696/
https://ncbi.nlm.nih.gov/pubmed/26661166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X15606463
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi