Regulation of retinal angiogenesis by phospholipase C-β3 signaling pathway

Angiogenesis has an essential role in many pathophysiologies. Here, we show that phospholipase C-β3 (PLC-β3) isoform regulates endothelial cell function and retinal angiogenesis. Silencing of PLC-β3 in human umbilical vein endothelial cells (HUVECs) significantly delayed proliferation, migration and...

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Bibliografiske detaljer
Udgivet i:Exp Mol Med
Main Authors: Ha, Jung Min, Baek, Seung Hoon, Kim, Young Hwan, Jin, Seo Yeon, Lee, Hye Sun, Kim, Sun Ja, Shin, Hwa Kyoung, Lee, Dong Hyung, Song, Sang Heon, Kim, Chi Dae, Bae, Sun Sik
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929692/
https://ncbi.nlm.nih.gov/pubmed/27311705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2016.39
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