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S-adenosylmethionine reduces airway inflammation and fibrosis in a murine model of chronic severe asthma via suppression of oxidative stress

Increased oxidative stress has an important role in asthmatic airway inflammation and remodeling. A potent methyl donor, S-adenosylmethionine (SAMe), is known to protect against tissue injury and fibrosis through modulation of oxidative stress. The aim of this study was to evaluate the effect of SAM...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Exp Mol Med
Κύριοι συγγραφείς: Yoon, Sun-Young, Hong, Gyong Hwa, Kwon, Hyouk-Soo, Park, Sunjoo, Park, So Young, Shin, Bomi, Kim, Tae-Bum, Moon, Hee-Bom, Cho, You Sook
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group 2016
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929690/
https://ncbi.nlm.nih.gov/pubmed/27256110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2016.35
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