S-adenosylmethionine reduces airway inflammation and fibrosis in a murine model of chronic severe asthma via suppression of oxidative stress

Increased oxidative stress has an important role in asthmatic airway inflammation and remodeling. A potent methyl donor, S-adenosylmethionine (SAMe), is known to protect against tissue injury and fibrosis through modulation of oxidative stress. The aim of this study was to evaluate the effect of SAM...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Yoon, Sun-Young, Hong, Gyong Hwa, Kwon, Hyouk-Soo, Park, Sunjoo, Park, So Young, Shin, Bomi, Kim, Tae-Bum, Moon, Hee-Bom, Cho, You Sook
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929690/
https://ncbi.nlm.nih.gov/pubmed/27256110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2016.35
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