Dual-faced SH3BGRL: oncogenic in mice, tumor suppressive in humans

Despite abundant data supporting c-Src as a metastasis-promoting oncogene, activating mutations of c-Src are rare. This suggests that trans-interacting proteins may have a critical role in regulating c-Src activation. Here, we first report the discovery of Src homology 3 (SH3) domain-binding glutami...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Wang, H, Liu, B, Al-Aidaroos, A Q O, Shi, H, Li, L, Guo, K, Li, J, Tan, B C P, Loo, J M, Tang, J P, Thura, M, Zeng, Q
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929482/
https://ncbi.nlm.nih.gov/pubmed/26455318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.391
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