Altered development in GABA co‐release shapes glycinergic synaptic currents in cultured spinal slices of the SOD1(G93A) mouse model of amyotrophic lateral sclerosis

KEY POINTS: Increased environmental risk factors in conjunction with genetic susceptibility have been proposed with respect to the remarkable variations in mortality in amyotrophic lateral sclerosis (ALS). In vitro models allow the investigation of the genetically modified counter‐regulator of moton...

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Publicat a:J Physiol
Autors principals: Medelin, Manuela, Rancic, Vladimir, Cellot, Giada, Laishram, Jummi, Veeraraghavan, Priyadharishini, Rossi, Chiara, Muzio, Luca, Sivilotti, Lucia, Ballerini, Laura
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Neuroscience ‐ Neurobiology of Disease
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929329/
https://ncbi.nlm.nih.gov/pubmed/27098371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP272382
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