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Efficient and Reliable Production of Vectors for the Study of the Repair, Mutagenesis, and Phenotypic Consequences of Defined DNA Damage Lesions in Mammalian Cells

Mammalian cells are constantly and unavoidably exposed to DNA damage from endogenous and exogenous sources, frequently to the detriment of genomic integrity and biological function. Cells acquire a large number of chemically diverse lesions per day, and each can have a different genetic fate and bio...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Petrova, Lucy, Gran, Christine, Bjoras, Magnar, Doetsch, Paul W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4928824/
https://ncbi.nlm.nih.gov/pubmed/27362559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158581
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