Phenytoin intoxication during concurrent diazepam therapy
Phenytoin elimination is a saturable process obeying Michaelis-Menten kinetics. Plasma phenytoin levels are not related linearly to dose, and small changes in enzyme activity produced by concurrent drug therapy could alter plasma levels. Two cases of phenytoin intoxication associated with simultaneo...
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| Publicado no: | J Neurol Neurosurg Psychiatry |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMJ Publishing Group
1977
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC492863/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/599366/ https://ncbi.nlm.nih.govhttps://doi.org/10.1136/jnnp.40.9.890 |
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