Učitavanje...
p27(KIP1) and PTEN cooperate in myeloproliferative neoplasm tumor suppression in mice
PTEN acts as a phosphatase for PIP3 and negatively regulates the PI3K/AKT pathway, and p27(KIP1) is a cyclin-dependent kinase inhibitor that regulates the G1 to S-phase transition by binding to and regulating the activity of cyclin-dependent kinases. Genetic alterations of PTEN or CDKN1B (p27(KIP1))...
Spremljeno u:
| Izdano u: | Exp Hematol Oncol |
|---|---|
| Glavni autori: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2016
|
| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4928343/ https://ncbi.nlm.nih.gov/pubmed/27366593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-016-0047-0 |
| Oznake: |
Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!
|