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Expansion of amphibian intronless interferons revises the paradigm for interferon evolution and functional diversity

Interferons (IFNs) are key cytokines identified in vertebrates and evolutionary dominance of intronless IFN genes in amniotes is a signature event in IFN evolution. For the first time, we show that the emergence and expansion of intronless IFN genes is evident in amphibians, shown by 24–37 intronles...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sang, Yongming, Liu, Qinfang, Lee, Jinhwa, Ma, Wenjun, McVey, D. Scott, Blecha, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4928184/
https://ncbi.nlm.nih.gov/pubmed/27356970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29072
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