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Hotspot mutations delineating diverse mutational signatures and biological utilities across cancer types
BACKGROUND: An important step towards personalizing cancer treatment is to integrate heterogeneous evidences to catalog mutational hotspots that are biologically and therapeutically relevant and thus represent where targeted therapy would likely be beneficial. However, existing methods do not suffic...
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| Publicado no: | BMC Genomics |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4928158/ https://ncbi.nlm.nih.gov/pubmed/27356755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2727-x |
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