Small Glutamine-Rich Tetratricopeptide Repeat-Containing Protein Alpha (SGTA) Ablation Limits Offspring Viability and Growth in Mice

Small glutamine-rich tetratricopeptide repeat-containing protein α (SGTA) has been implicated as a co-chaperone and regulator of androgen and growth hormone receptor (AR, GHR) signalling. We investigated the functional consequences of partial and full Sgta ablation in vivo using Cre-lox Sgta-null mi...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Philp, Lisa K., Day, Tanya K., Butler, Miriam S., Laven-Law, Geraldine, Jindal, Shalini, Hickey, Theresa E., Scher, Howard I., Butler, Lisa M., Tilley, Wayne D.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4928056/
https://ncbi.nlm.nih.gov/pubmed/27358191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28950
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