Krüppel-Like Factor 4 Is a Regulator of Proinflammatory Signaling in Fibroblast-Like Synoviocytes through Increased IL-6 Expression

Human fibroblast-like synoviocytes play a vital role in joint synovial inflammation in rheumatoid arthritis (RA). Proinflammatory cytokines induce fibroblast-like synoviocyte activation and dysfunction. The inflammatory mediator Krüppel-like factor 4 is upregulated during inflammation and plays an i...

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Publicat a:Mediators Inflamm
Autors principals: Luo, Xinjing, Chen, Jie, Ruan, Jianwei, Chen, Yongfeng, Mo, Xuanrong, Xie, Jiangwen, Lv, Guoju
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4928008/
https://ncbi.nlm.nih.gov/pubmed/27413250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/1062586
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