Phase I Study of Everolimus in Combination with Gemcitabine and Split-Dose Cisplatin in Advanced Urothelial Carcinoma

BACKGROUND: Cisplatin-based combination chemotherapy is standard first-line treatment for patients with advanced urothelial carcinoma (UC). Molecular profiling studies reveal that the PI3K/AKT/mTOR pathway is altered in a significant percentage of UCs. OBJECTIVE: We conducted a phase I trial to eval...

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Bibliografiske detaljer
Udgivet i:Bl Cancer
Main Authors: Abida, Wassim, Milowsky, Matthew I., Ostrovnaya, Irina, Gerst, Scott R., Rosenberg, Jonathan E., Voss, Martin H., Apolo, Andrea B., Regazzi, Ashley M., McCoy, Asia S., Boyd, Mariel E., Bajorin, Dean F.
Format: Artigo
Sprog:Inglês
Udgivet: IOS Press 2016
Fag:
Research Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4927849/
https://ncbi.nlm.nih.gov/pubmed/27376132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/BLC-150038
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