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Loss- and Gain-of-function Approach to Investigate Early Cell Fate Determinants in Preimplantation Mouse Embryos

Gene silencing and overexpression techniques are instrumental for the identification of genes involved in embryonic development. Direct target gene modification in preimplantation embryos provides a means to study the underlying mechanisms of genes implicated in, for instance, cellular differentiati...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Lee, Jae H., Cho, Yong II, Choi, Sung S., Kim, Hae-Won, Min, Churl K., Lee, Sang J.
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4927766/
https://ncbi.nlm.nih.gov/pubmed/27341639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/53696
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