A molecular mechanism for pyrimidine and purine nucleotide control of aspartate transcarbamoylase.
CTP (ATP) binding to the T or R state causes reorientation of several key residues and results in a decrease (increase) in the size of the nucleotide binding site and a related decrease (increase) in the extension of the outer parts of the dimer of the regulatory chains, R1 and R6. As a result, CTP...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1992
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49275/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1608935/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.12.5281 |
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