Loss of CENP-F results in distinct microtubule-related defects without chromosomal abnormalities

Microtubule (MT)-binding centromere protein F (CENP-F) was previously shown to play a role exclusively in chromosome segregation during cellular division. Many cell models of CENP-F depletion show a lag in the cell cycle and aneuploidy. Here, using our novel genetic deletion model, we show that CENP...

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Библиографические подробности
Опубликовано в: :Mol Biol Cell
Главные авторы: Pfaltzgraff, Elise R., Roth, Gretchen M., Miller, Paul M., Gintzig, Anneelizabeth G., Ohi, Ryoma, Bader, David M.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Cell Biology 2016
Предметы:
Brief Reports
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4927273/
https://ncbi.nlm.nih.gov/pubmed/27146114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-12-0848
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