Combination of Controllably Released Platelet Rich Plasma Alginate Beads and Bone Morphogenic Protein-2 Gene-Modified Mesenchymal Stem Cells for Bone Regeneration

BACKGROUND: Platelet rich plasma (PRP) consists of platelet derived growth factor (PDGF) and Transforming growth factor-beta (TGF-β) that increase cell proliferation of mesenchymal stem cells (MSCs), whereas, bone morphogenic Protein-2 (BMP2) promotes osteogenic differentiation of MSCs. However, the...

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Veröffentlicht in:J Periodontol
Hauptverfasser: Fernandes, Gabriela, Wang, Changdong, Yuan, Xue, Liu, Zunpeng, Dziak, Rosemary, Yang, Shuying
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4927087/
https://ncbi.nlm.nih.gov/pubmed/26745613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1902/jop.2016.150487
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