Inhibitor of NFκB Kinase Subunit 2 Blockade Hinders the Initiation but Aggravates the Progression of Crescentic GN

The NFκB transcription factor family facilitates the activation of dendritic cells (DCs) and CD4(+) T helper (Th) cells, which are important for protective adaptive immunity. Inappropriate activation of these immune cells may cause inflammatory disease, and NFκB inhibitors are promising anti–inflamm...

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Опубликовано в: :J Am Soc Nephrol
Главные авторы: Gotot, Janine, Piotrowski, Eveline, Otte, Martin S., Tittel, André P., Linlin, Guo, Yao, Chen, Ziegelbauer, Karl, Panzer, Ulf, Garbi, Natalio, Kurts, Christian, Thaiss, Friedrich
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Nephrology 2016
Предметы:
Brief Communications
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926984/
https://ncbi.nlm.nih.gov/pubmed/26574045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015060699
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