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Mobilization of Intracellular Copper by Gossypol and Apogossypolone Leads to Reactive Oxygen Species-Mediated Cell Death: Putative Anticancer Mechanism

There is compelling evidence that serum, tissue and intracellular levels of copper are elevated in all types of cancer. Copper has been suggested as an important co-factor for angiogenesis. It is also a major metal ion present inside the nucleus, bound to DNA bases, particularly guanine. We have ear...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Int J Mol Sci
Κύριοι συγγραφείς: Zubair, Haseeb, Azim, Shafquat, Khan, Husain Yar, Ullah, Mohammad Fahad, Wu, Daocheng, Singh, Ajay Pratap, Hadi, Sheikh Mumtaz, Ahmad, Aamir
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: MDPI 2016
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926505/
https://ncbi.nlm.nih.gov/pubmed/27331811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17060973
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