Bioavailability of an R-α-Lipoic Acid/γ-Cyclodextrin Complex in Healthy Volunteers

R-α-lipoic acid (R-LA) is a cofactor of mitochondrial enzymes and a very strong antioxidant. R-LA is available as a functional food ingredient but is unstable against heat or acid. Stabilized R-LA was prepared through complexation with γ-cyclodextrin (CD), yielding R-LA/CD. R-LA/CD was orally admini...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Ikuta, Naoko, Okamoto, Hinako, Furune, Takahiro, Uekaji, Yukiko, Terao, Keiji, Uchida, Ryota, Iwamoto, Kosuke, Miyajima, Atsushi, Hirota, Takashi, Sakamoto, Norihiro
Format: Artigo
Language:Inglês
Published: MDPI 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926482/
https://ncbi.nlm.nih.gov/pubmed/27314343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17060949
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