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Stable Toll-Like Receptor 10 Knockdown in THP-1 Cells Reduces TLR-Ligand-Induced Proinflammatory Cytokine Expression

Toll-like receptor 10 (TLR10) is the only orphan receptor whose natural ligand and function are unknown among the 10 human TLRs. In this study, to test whether TLR10 recognizes some known TLR ligands, we established a stable TLR10 knockdown human monocytic cell line THP-1 using TLR10 short hairpin R...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Main Authors: Le, Hai Van, Kim, Jae Young
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926393/
https://ncbi.nlm.nih.gov/pubmed/27258267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17060859
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