Genomic alterations underlie a pan-cancer metabolic shift associated with tumour hypoxia

BACKGROUND: Altered metabolism is a hallmark of cancer. However, the role of genomic changes in metabolic genes driving the tumour metabolic shift remains to be elucidated. Here, we have investigated the genomic and transcriptomic changes underlying this shift across ten different cancer types. RESU...

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Bibliografische gegevens
Gepubliceerd in:Genome Biol
Hoofdauteurs: Haider, Syed, McIntyre, Alan, van Stiphout, Ruud G. P. M., Winchester, Laura M., Wigfield, Simon, Harris, Adrian L., Buffa, Francesca M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2016
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926297/
https://ncbi.nlm.nih.gov/pubmed/27358048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-0999-8
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