Phosphorylated-insulin growth factor I receptor (p-IGF1R) and metalloproteinase-3 (MMP3) expression in advanced gastrointestinal stromal tumors (GIST). A GEIS 19 study

BACKGROUND: Most GISTs have mutations in KIT or PDGFRA. Patients with advanced GIST with KIT exon 9, PDGFRA mutation or WT for KIT and PDGFRA have a worse progression-free survival (PFS) compared to patients with KIT exon 11 mutated tumors. We evaluated the immunohistochemical (IHC) expression of p-...

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Detalhes bibliográficos
Publicado no:Clin Sarcoma Res
Main Authors: Maurel, Joan, López-Pousa, Antonio, Calabuig, Silvia, Bagué, Silvia, del Muro, Xavier Garcia, Sanjuan, Xavier, Rubió-Casadevall, Jordi, Cuatrecasas, Miriam, Martinez-Trufero, Javier, Horndler, Carlos, Fra, Joaquin, Valverde, Claudia, Redondo, Andrés, Poveda, Andrés, Sevilla, Isabel, Lainez, Nuria, Rubini, Michele, García-Albéniz, Xabier, Martín-Broto, Javier, de Alava, Enrique
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926286/
https://ncbi.nlm.nih.gov/pubmed/27358721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13569-016-0050-6
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