A Designed “Nested” Dimer of Cyanovirin-N Increases Antiviral Activity

Cyanovirin-N (CV-N) is an antiviral lectin with potent activity against enveloped viruses, including HIV. The mechanism of action involves high affinity binding to mannose-rich glycans that decorate the surface of enveloped viruses. In the case of HIV, antiviral activity of CV-N is postulated to req...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Woodrum, Brian W., Maxwell, Jason, Allen, Denysia M., Wilson, Jennifer, Krumpe, Lauren R.H., Bobkov, Andrey A., Hill, R. Blake, Kibler, Karen V., O’Keefe, Barry R., Ghirlanda, Giovanna
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926178/
https://ncbi.nlm.nih.gov/pubmed/27275831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v8060158
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