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Accurate Measurement of the Effects of All Amino-Acid Mutations on Influenza Hemagglutinin

Influenza genes evolve mostly via point mutations, and so knowing the effect of every amino-acid mutation provides information about evolutionary paths available to the virus. We and others have combined high-throughput mutagenesis with deep sequencing to estimate the effects of large numbers of mut...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Doud, Michael B., Bloom, Jesse D.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926175/
https://ncbi.nlm.nih.gov/pubmed/27271655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v8060155
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