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Use of VacA as a Vaccine Antigen

One of the major toxins secreted by H. pylori is the Vacuolating cytotoxin A (VacA) named after its ability to induce the formation of “vacuole”-like membrane vesicles in the cytoplasm of gastric cells. VacA has been associated with the disruption of mitochondrial functions, stimulation of apoptosis...

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Bibliographic Details
Published in:Toxins (Basel)
Main Authors: Moyat, Mati, Velin, Dominique
Format: Artigo
Language:Inglês
Published: MDPI 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926147/
https://ncbi.nlm.nih.gov/pubmed/27338474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins8060181
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